Uptake of local anaesthetics: Movement of ethanol into frog sciatic nerve
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چکیده
منابع مشابه
Potassium Fluxes in Desheathed Frog Sciatic Nerve
Desheathed frog (R. pipiens) sciatic nerves were soaked in Na-deficient solutions, and measurements were made of their Na and K contents and of the movements of K(42). When a nerve is in Ringer's solution, the Na fluxes are equal to the K fluxes, and about 75 per cent of the K influx is due to active transport. The Na content and the Na efflux are linearly related to the Na concentration of the...
متن کاملSodium Fluxes in Desheathed Frog Sciatic Nerve
Desheathed frog (R. pipiens) sciatic nerves were soaked in solutions that contained ouabain or NaN(3), in K-free solutions, or in K- and Ca-free solutions. Then, the nerves were allowed to recover in standard Ringer's solution. At various times during the soaking periods, some nerves were analyzed for Na and K, and estimates were made of the influx and efflux of Na(22). While a nerve was soakin...
متن کاملAC impedance of the perineurium of the frog sciatic nerve.
The AC impedance of the isolated perineurium of the frog sciatic nerve was examined at frequencies from 2 Hz to 100 kHz. A Nyquist plot of the imaginary and real components of the impedance demonstrated more than 1 capacitative element, and a DC resistance of 478 +/- 34 (SEM, n = 27) omega cm2. Transperineurial potential in the absence of externally applied current was 0.0 +/- 0.5 mV. The imped...
متن کاملP21: Local Administration of Methylprednisolone Laden Hydrogel Enhances Functional Recovery of Transected Sciatic Nerve in Rat
The repair of peripheral nerve injuries is still one of the most challenging tasks and concerns in neurosurgery. Effect of methylprednisolone-laden hydrogel loaded into a chitosan conduit on the functional recovery of peripheral nerve using a rat sciatic nerve regeneration model was assessed. A 10-mm sciatic nerve defect was bridged using a chitosan conduit (CHIT/CGP-Hydrogel) filled with CGP-h...
متن کاملThe Compound Action Potential (CAP) of the Frog Sciatic Nerve
a) In mammals, large peripheral nerves, for example the vagus, the sciatic and the ulnar typically are bundles of thousands of individual axons enclosed in a loose connective tissue sheath, the Epineurium. Within the Epineurium, the axons are grouped in fascicles, encased in a more structured epithelial sheath (the perineurium). Each axon is surrounded by a thin connective tissue sheath, the en...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1975
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03004974